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Once new entrepreneurial businesses get established, they create opportunities to extend their supply chains upstream and downstream in the region. This brings more economic activity to the region, strengthens the skills of the workforce, accelerates innovation and improves profitability by cutting shipping and logistics costs. For example, a cluster of beer breweries has grown up in and around Asheville, the region's largest city, which now hosts roughly 15 local breweries. With the breweries established, the brewing industry can support local upstream businesses in grain and malt production. Downstream, the brewery cluster has forged an alliance to take the spent grain left after brewing and provide it to local farms where it serves as a low cost, highly nutritious feed for livestock.
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